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Article

Somatic control of germline sexual development is mediated by the JAK/STAT pathway.

Nature - 28 Jul 2005

Wawersik Matthew, Milutinovich Allison, Casper Abbie L, Matunis Erika, Williams Brian, Van Doren Mark

Abstract excerpt

Germ cells must develop along distinct male or female paths to produce the sperm or eggs required for sexual reproduction. In both mouse and Drosophila, the sexual identity of germ cells is influenced by the sex of the surrounding somatic tissue (for example, refs 1, 2, reviewed in refs 3, 4); however, little is known about how the soma controls germline sex determination. Here we show that the janus...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16049490
DOI: 10.1038/nature03849
PMCID: PMC1421378

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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