Pathways of viral gene expression during acute neuronal infection with HSV-1.

doi:10.1016/0042-6822(92)90690-q

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Article

Pathways of viral gene expression during acute neuronal infection with HSV-1.

Virology - 1 Jul 1992

Margolis T P, Sedarati F, Dobson A T, Feldman L T, Stevens J G

Abstract excerpt

Pathways of viral gene expression were investigated during the acute phase of sensory ganglionic infection with HSV-1. To facilitate these studies we constructed KOS/62-3, an HSV-1 vector in which the Escherichia coli lac-Z gene was inserted behind both copies of the promoter for the viral latenc...

Topics

Acute Disease
Acyclovir
Animals
Antigens, Viral
Cytarabine
DNA, Viral
Female
Ganglia, Spinal
Herpes Simplex
Mice
Neurons
Phenotype
Recombinant Proteins
Tissue Distribution
Virus Replication
beta-Galactosidase

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