Article
Pathways of viral gene expression during acute neuronal infection with HSV-1.
Virology - 1 Jul 1992
Margolis T P, Sedarati F, Dobson A T, Feldman L T, Stevens J G
Abstract excerpt
Pathways of viral gene expression were investigated during the acute phase of sensory ganglionic infection with HSV-1. To facilitate these studies we constructed KOS/62-3, an HSV-1 vector in which the Escherichia coli lac-Z gene was inserted behind both copies of the promoter for the viral latency-associated transcripts. Following footpad inoculation of mice with the virus, acutely infected dorsal root ganglion...
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