Article
Role of herpes simplex virus thymidine kinase expression in viral pathogenesis and latency.
Intervirology - 1 Jan 1991
Tenser R B
Abstract excerpt
Herpes simplex virus (HSV) thymidine kinase (TK) expression and the HSV TK gene have been evaluated in studies of gene control, as well as in animal and human studies of viral pathogenesis, including HSV latency. In investigations of the biological role of HSV TK, enzyme expression was noted to be important for HSV infection of nonreplicating cells in culture; and, in experimental animal studies, HSV TK was shown...
Topics
- Animals
- Humans
- Mutation
- RNA, Viral
- Simplexvirus
- Thymidine Kinase
- Time Factors
- Virus Activation