Article
Global gene expression and the role of sigma factors in Neisseria gonorrhoeae in interactions with epithelial cells.
Infection and immunity - 1 Aug 2005
Du Ying, Lenz Jonathan, Arvidson Cindy Grove
Abstract excerpt
Like many bacterial pathogens, Neisseria gonorrhoeae must adapt to environmental changes in order to successfully colonize and proliferate in a new host. Modulation of gene expression in response to environmental signals is an efficient mechanism used by bacteria to achieve this goal. Using DNA microarrays and a tissue culture model for gonococcal infection, we examined global changes in gene expression in N....
Topics
- Bacterial Adhesion
- Epithelial Cells
- Gene Expression Profiling
- Gonorrhea
- Heat-Shock Proteins
- Humans
- Mutation
- Neisseria gonorrhoeae
- Reverse Transcriptase Polymerase Chain Reaction
- Sigma Factor
- Transcription Factors
- Up-Regulation