Article
Identification of a new OmpA-like protein in Neisseria gonorrhoeae involved in the binding to human epithelial cells and in vivo colonization.
Molecular microbiology - 1 Jun 2007
Serino Laura, Nesta Barbara, Leuzzi Rosanna, Fontana Maria Rita, Monaci Elisabetta, Mocca Brian T, Cartocci Elena, Masignani Vega, Jerse Ann E, Rappuoli Rino, Pizza Mariagrazia
Abstract excerpt
Outer membrane protein As (OmpAs) are highly conserved proteins within the Enterobacteriaceae family. OmpA contributes to the maintenance of structural membrane integrity and invasion into mammalian cells. In Escherichia coli K1 OmpA also contributes to serum resistance and is involved in the virulence of the bacterium. Here we describe the identification of an OmpA-like protein in Neisseria gonorrhoeae...
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