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Article

Human p53 tumor suppressor gene (TP53) and schizophrenia: case-control and family studies.

Neuroscience letters - 18 Nov 2005

Ni Xingqun, Trakalo Joseph, Valente Jose, Azevedo Maria H, Pato Michelle T, Pato Carlos N, Kennedy James L

Abstract excerpt

The human p53 tumor suppressor gene (TP53) is considered as a candidate susceptibility gene for schizophrenia because of its functions in neurodevelopment. To test for an association between TP53 and schizophrenia, both the case-control study and the transmission disequilibrium test (TDT) were performed on genotype data from eight polymorphisms in TP53. Our samples included 286 Toronto schizophrenia cases and 264...

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PMID: 16039051
DOI: 10.1016/j.neulet.2005.06.050

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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