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Article

A Cre gene directed by a human TSPY promoter is specific for germ cells and neurons

1 Jan 2005

Abstract excerpt

The testis-specific protein Y-encoded (TSPY) gene is a candidate for the gonadoblastoma locus on the Y chromosome and is expressed in normal testicular germ cells and gonadoblastoma cells of XY sex-reversed females. Although TSPY expression has been demonstrated in gonadoblastoma tissues, it is uncertain if such expression is involved in a causative or consequential event of the oncogenic process. We postulate...

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PMID: 16035036
DOI: 10.1002/gene.20147

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