Article
The yeast RNA1 protein, necessary for RNA processing, is homologous to the human ribonuclease/angiogenin inhibitor (RAI).
Molecular & general genetics : MGG - 1 May 1992
Schneider R, Schweiger M
Abstract excerpt
Mutations in the RNA1 gene of Saccharomyces cerevisiae, which encodes an essential cytosolic protein, affect the production and processing of all major classes of RNA. The mechanisms underlying these effects are not at all understood. Detailed comparative sequence analyses revealed that the RNA1 protein belongs to a superfamily, the members of which contain repetitive "leucine-rich motifs" (LRM). Within this...
Topics
- Amino Acid Sequence
- Fungal Proteins
- GTPase-Activating Proteins
- Humans
- Molecular Sequence Data
- Mutation
- Proteins
- RNA Processing, Post-Transcriptional
- Repetitive Sequences, Nucleic Acid
- Ribonuclease, Pancreatic