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Article

Cross-talk between snurportin1 subdomains.

Molecular biology of the cell - 1 Oct 2005

Ospina Jason K, Gonsalvez Graydon B, Bednenko Janna, Darzynkiewicz Edward, Gerace Larry, Matera A Gregory

Abstract excerpt

The initial steps of spliceosomal small nuclear ribonucleoprotein (snRNP) maturation take place in the cytoplasm. After formation of an Sm-core and a trimethylguanosine (TMG) cap, the RNPs are transported into the nucleus via the import adaptor snurportin1 (SPN) and the import receptor importin-beta. To better understand this process, we identified SPN residues that are required to mediate interactions with TMG...

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Topics

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Share to Active Transport, Cell Nucleus
Share to beta Karyopherins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Exportin 1 Protein

Share to Fatty Acids, Unsaturated

Share to Karyopherins

Share to Motor Neurons

Share to Receptors, Cytoplasmic and Nuclear

Share to Ribonucleoprotein, U2 Small Nuclear

Source

Open in PubMed Open full text

Identifiers

PMID: 16030253
DOI: 10.1091/mbc.e05-04-0316
PMCID: PMC1237072

Genes

SPN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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