Article
Identification of a D-glycero-D-manno-heptosyltransferase gene from Helicobacter pylori.
Journal of bacteriology - 1 Aug 2005
Hiratsuka Koji, Logan Susan M, Conlan J Wayne, Chandan Vandana, Aubry Annie, Smirnova Natalia, Ulrichsen Heather, Chan Kenneth H N, Griffith Douglas W, Harrison Blair A, Li Jianjun, Altman Eleonora
Abstract excerpt
We have identified a Helicobacter pylori d-glycero-d-manno-heptosyltransferase gene, HP0479, which is involved in the biosynthesis of the outer core region of H. pylori lipopolysaccharide (LPS). Insertional inactivation of HP0479 resulted in formation of a truncated LPS molecule lacking an alpha-1,6-glucan-, dd-heptose-containing outer core region and O-chain polysaccharide. Detailed structural analysis of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
