Article
Colonization of gerbils with Helicobacter pylori O-chain-deficient mutant SS1 HP0826::Kan results in gastritis and is associated with de novo synthesis of extended homopolymers.
Pathogens and disease - 1 Mar 2013
Chandan Vandana, Jeremy Anthony H T, Dixon Michael F, Altman Eleonora, Crabtree Jean E
Abstract excerpt
The O-chain polysaccharide of Helicobacter pylori is important for colonization and generation of chronic gastritis in mice. There are marked host differences in the development of H. pylori-induced gastric pathology in mice and gerbils. To investigate the role of the O-chain polysaccharide of H. pylori in colonization and gastritis in Mongolian gerbils, inoculation by oral gavage with H. pylori strain SS1 and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.