Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact of FLT3 mutations and promyelocytic leukaemia-breakpoint on clinical characteristics and prognosis in acute promyelocytic leukaemia.

British journal of haematology - 1 Jul 2005

Kuchenbauer Florian, Schoch Claudia, Kern Wolfgang, Hiddemann Wolfgang, Haferlach Torsten, Schnittger Susanne

Abstract excerpt

In the present study 170 newly diagnosed acute promyelocytic leukaemia patients (M3: n = 121; M3v: n = 49) were molecularly characterised with respect to PML breakpoint and additional molecular mutations. In total, 83 patients were positive for bcr1 (49%), five for bcr2 (3%) and 82 for bcr3 (48%)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease-Free Survival
Share to fms-Like Tyrosine Kinase 3
Share to Leukemia, Promyelocytic, Acute

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukocyte Count

Share to Oncogene Proteins, Fusion

Share to Protein-Tyrosine Kinases

Share to Receptor Protein-Tyrosine Kinases

Share to Survival Rate

Source

Identifiers

PMID: 16029447
DOI: 10.1111/j.1365-2141.2005.05595.x

Genes

FLT3
PML
KIT
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16029447-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of FLT3 mutations and promyelocytic leukaemia-breakpoint on clinical characteristics and prognosis in acute promyelocytic leukaemia.PMID 16029447Read ↗

Prognostic implication of FLT3 and Ras gene mutations in patients with acute promyelocytic leukemia (APL): a retrospective study from the European APL Group.Semantic proximity Read ↗

Clinicopathological Significance of Common Genetic Alterations in Patients With Acute Promyelocytic Leukemia.Semantic proximity Read ↗

Prognostic implication of FLT3 and N-RAS gene mutations in acute myeloid leukemia.Semantic proximity Read ↗

Prognostic significance of additional cytogenetic abnormalities and FLT3 mutations in acute promyelocytic leukemia.Semantic proximity Read ↗

Clinical outcome of patients with acute promyelocytic leukemia and FLT3 mutations.Semantic proximity Read ↗

FLT-3 aberrations in acute promyelocytic leukaemia: clinicopathological associations and prognostic impact.Semantic proximity Read ↗

Alterations of the FLT3 gene in acute promyelocytic leukemia: association with diagnostic characteristics and analysis of clinical outcome in patients treated with the Italian AIDA protocol.Semantic proximity Read ↗

Prognostic Significance of bcr-1 and bcr-3 Isoforms of PML-RARA and FLT3-ITD in Patients With Acute Promyelocytic LeukemiaSemantic proximity Read ↗

Immunophenotype of adult and childhood acute promyelocytic leukaemia: correlation with morphology, type of PML gene breakpoint and clinical outcome. A cooperative Italian study on 196 casesSemantic proximity Read ↗

Relationship between FLT3 mutation status, biologic characteristics, and response to targeted therapy in acute promyelocytic leukemia.Semantic proximity Read ↗

Inferior prognostic outcome in acute promyelocytic leukemia with alterations of FLT3 gene.Semantic proximity Read ↗

Prognostic value of FLT3 mutations in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline monochemotherapy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.