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Article

Isoform-specific early trafficking of AMPA receptor flip and flop variants.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 25 Oct 2006

Coleman Sarah K, Möykkynen Tommi, Cai Chunlin, von Ossowski Lotta, Kuismanen Esa, Korpi Esa R, Keinänen Kari

Abstract excerpt

Flip and flop splice variants of AMPA receptor subunits are expressed in distinct but partly overlapping patterns and impart different desensitization kinetics to cognate receptor channels. In the absence of specific antibodies, isoform-specific differences in trafficking or localization of native flip and flop subunits remain uncharacterized. We report that in several transfected cell lines, transport of...

Topics

Animals
COS Cells
Cells, Cultured
Chlorocebus aethiops
DNA, Recombinant
Genetic Variation
Humans
Mice
Protein Isoforms
Protein Transport
Rats

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, AMPA

Receptors, Glutamate

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Open in PubMed Open full text

Identifiers

PMID: 17065461
DOI: 10.1523/JNEUROSCI.2301-06.2006
PMCID: PMC6674648

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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