Insulin-like growth factor-1 gene splice variants as markers of muscle damage in levator ani muscle after the first vaginal delivery.

doi:10.1016/j.ajog.2004.12.088

Article

Insulin-like growth factor-1 gene splice variants as markers of muscle damage in levator ani muscle after the first vaginal delivery.

American journal of obstetrics and gynecology - 1 Jul 2005

Cortes Eduardo, te Fong Lan F Wong, Hameed Mahjabeen, Harridge Stephen, Maclean Allan, Yang Shi Yu, Reid Wendy M, Goldspink Geoffrey

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OBJECTIVE: Studies in animals and human muscle have demonstrated differential splicing of the insulin-like growth factor-1 gene in response to mechanical strain and damage. We conducted a study on the expression of insulin-like growth factor-1 splice variants in the levator ani muscle after the first vaginal delivery. STUDY DESIGN: Ten women were recruited after the first vaginal delivery. Biopsy specimens were...

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Insulin-like growth factor-1 gene splice variants as markers of muscle damage in levator ani muscle after the first vaginal delivery.

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