Article

Repeated birth injuries lead to pelvic floor muscle dysfunction and impairment in regeneration

2022-05-02

Abstract excerpt

<h4>Objectives</h4> Childbirth is a key risk factor for pelvic floor muscle (PFM) injury and dysfunction, and subsequent pelvic floor disorders (PFDs). Multiparity further exacerbates these risks. Using the pre-clinical rat model of simulated birth injury (SBI), we previously identified that an SBI leads to PFM atrophy and fibrosis. We hypothesized that multiple SBIs further overwhelm PFM regenerative capacity, l...

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Literature Corpus work: 2b6f1ed4-6b5c-58d1-a589-9580b2b11c5a
DOI: 10.1101/2022.05.02.490259

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