Article
Progestin activation of nongenomic pathways via cross talk of progesterone receptor with estrogen receptor beta induces proliferation of endometrial stromal cells.
Molecular endocrinology (Baltimore, Md.) - 1 Dec 2005
Vallejo Griselda, Ballaré Cecilia, Barañao José Lino, Beato Miguel, Saragüeta Patricia
Abstract excerpt
Uterine decidualization is characterized by stromal cell proliferation and differentiation, which are controlled by ovarian hormones estradiol and progesterone. Here we report that the proliferative response of UIII rat uterine stromal cells to a short treatment with progestins requires active progesterone receptor (PR) and estrogen receptor beta (ERbeta) as well as a rapid and transient activation of Erk1-2 and...
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