Article
Transcriptional profiling of tissue plasticity: role of shifts in gene expression and technical limitations.
Journal of applied physiology (Bethesda, Md. : 1985) - 1 Aug 2005
Flück Martin, Däpp Christoph, Schmutz Silvia, Wit Ernst, Hoppeler Hans
Abstract excerpt
Reprogramming of gene expression has been recognized as a main instructive modality for the adjustments of tissues to various kinds of stress. The recent application of gene expression profiling has provided a powerful tool to elucidate the molecular pathways underlying such tissue remodeling. However, the biological interpretations of expression profiling results critically depend on normalization of transcript...
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