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Article

Eya 1 acts as a critical regulator for specifying the metanephric mesenchyme.

Developmental biology - 15 Aug 2005

Sajithlal Gangadharan, Zou Dan, Silvius Derek, Xu Pin-Xian

Abstract excerpt

Although it is well established that the Gdnf-Ret signal transduction pathway initiates metanephric induction, no single regulator has yet been identified to specify the metanephric mesenchyme or blastema within the intermediate mesoderm, the earliest step of metanephric kidney development and the molecular mechanisms controlling Gdnf expression are essentially unknown. Previous studies have shown that a loss of...

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Identifiers

PMID: 16018995
DOI: 10.1016/j.ydbio.2005.05.029
PMCID: PMC3876955

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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