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Article

Eya 1 acts as a critical regulator for specifying the metanephric mesenchyme.

Developmental biology - 15 Aug 2005

Sajithlal Gangadharan, Zou Dan, Silvius Derek, Xu Pin-Xian

Abstract excerpt

Although it is well established that the Gdnf-Ret signal transduction pathway initiates metanephric induction, no single regulator has yet been identified to specify the metanephric mesenchyme or blastema within the intermediate mesoderm, the earliest step of metanephric kidney development and th...

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Identifiers

PMID: 16018995
DOI: 10.1016/j.ydbio.2005.05.029
PMCID: PMC3876955

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16018995-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Eya 1 acts as a critical regulator for specifying the metanephric mesenchyme.PMID 16018995Read ↗

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Six1 and Six4 are essential for Gdnf expression in the metanephric mesenchyme and ureteric bud formation, while Six1 deficiency alone causes mesonephric-tubule defectsSemantic proximity Read ↗

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