Article
Protease inhibitor (Pi) locus, fertility and twinning.
Human genetics - 1 May 1992
Boomsma D I, Frants R R, Bank R A, Martin N G
Abstract excerpt
In a sample of 160 Dutch twin pairs and their parents, we found that mothers of dizygotic twins had frequencies of the S and Z alleles at the protease inhibitor (Pi) locus that were 3 times higher than a control sample. Mothers of identical twins also had a higher frequency of S than controls. The S allele may thus both increase ovulation rate and enhance the success of multiple pregnancies. There was also an...
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