Article
Physiological function of S-cone system is not enhanced in rd7 mice.
Experimental eye research - 1 Dec 2005
Ueno Shinji, Kondo Mineo, Miyata Kentaro, Hirai Toshie, Miyata Takaki, Usukura Jiro, Nishizawa Yuji, Miyake Yozo
Abstract excerpt
The rd7mouse is a mutant mouse with a relatively late development of retinal degeneration. Earlier studies have shown that rd7 mice have a distinctive pattern of retinal dysplasia with an increased number of cone cells, particularly those with S (short wavelength)-opsin immunoreactivity. These alterations of the rd7 retina are caused by a mutation in the photoreceptor cell-specific nuclear receptor gene, Nr2e3,...
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