Article
Two hybridization events define the population structure of Trypanosoma cruzi.
Genetics - 1 Oct 2005
Westenberger Scott J, Barnabé Christian, Campbell David A, Sturm Nancy R
Abstract excerpt
Genetic variation in Trypanosoma cruzi is likely a key determinant in transmission and pathogenesis of Chagas disease. We have examined nine loci as markers for the extant T. cruzi strains. Four distinct alleles were found for each locus, corresponding to the sequence classes present in the homozygous discrete typing units (DTUs) I, IIa, IIb, and IIc. The alleles in DTUs IIa and IIc showed a spectrum of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
