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Article

Structural genomics of human proteins – target selection and generation of a public catalogue of expression clones

5 Jul 2005

Abstract excerpt

BACKGROUND: The availability of suitable recombinant protein is still a major bottleneck in protein structure analysis. The Protein Structure Factory, part of the international structural genomics initiative, targets human proteins for structure determination. It has implemented high throughput procedures for all steps from cloning to structure calculation. This article describes the selection of human target...

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PMID: 15998469
DOI: 10.1186/1475-2859-4-21

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