Article
Carcinogen exposure and gene promoter hypermethylation in bladder cancer.
Carcinogenesis - 1 Jan 2006
Marsit Carmen J, Karagas Margaret R, Danaee Hadi, Liu Mei, Andrew Angeline, Schned Alan, Nelson Heather H, Kelsey Karl T
Abstract excerpt
Tobacco smoking, certain occupational exposures, and exposure to inorganic arsenic in drinking water have been associated with the occurrence of bladder cancer. However, in these tumors the exposure-associated pattern of somatic alterations in genes in the causal pathway for disease has been poorly characterized. In particular, the mechanism by which arsenic induces bladder cancer and the effects of lower...
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