Article
The Jak2V617F mutation, PRV-1 overexpression, and EEC formation define a similar cohort of MPD patients.
Blood - 15 Oct 2005
Goerttler Philipp S, Steimle Cordula, März Edith, Johansson Peter L, Andreasson Björn, Griesshammer Martin, Gisslinger Heinz, Heimpel Hermann, Pahl Heike L
Abstract excerpt
Recently, a Jak2V617F mutation has been described in the vast majority of patients with polycythemia vera (PV) as well as in subsets of patients with essential thrombocythemia (ET) and idiopathic myelofibrosis (IMF). The question arises whether this mutation is observed in those patients with ET and IMF who have also displayed previously described molecular markers, notably the ability to form endogenous...
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