Article
Interruption of treatment with individual therapeutic drug classes in adults with multidrug-resistant HIV-1 infection.
The Journal of infectious diseases - 1 Nov 2005
Deeks Steven G, Hoh Rebecca, Neilands Torsten B, Liegler Teri, Aweeka Francesca, Petropoulos Christos J, Grant Robert M, Martin Jeffrey N
Abstract excerpt
BACKGROUND: Many antiretroviral-treated human immunodeficiency virus (HIV)-infected patients experience sustained immunologic and virologic benefit despite the presence of multidrug-resistant HIV. We hypothesized that the use of simplified regimens could maintain treatment benefit while preventing viral evolution and reducing drug-related toxicity and costs. METHODS: We conducted a 48-week nonrandomized study of...
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