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Article

In vitro preparation of prefibrillar intermediates of amyloid-beta and alpha-synuclein.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2005

Lashuel Hilal A, Grillo-Bosch Dolors

Abstract excerpt

Elucidating the structural properties of early intermediates (protofibrils) on the fibril formation pathway of Abeta and alpha-synuclein, the structural relationship among the different intermediates and their relationship to the structure of the amyloid fibrils is critical for understanding the roles of amyloid fibril formation in the pathogenesis of Alzheimer's and Parkinson's diseases. In this chapter we...

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PMID: 15980593
DOI: 10.1385/1-59259-874-9:019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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