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Article

Identification and characterization of key kinetic intermediates in amyloid beta-protein fibrillogenesis.

Journal of molecular biology - 5 Oct 2001

Kirkitadze M D, Condron M M, Teplow D B

Abstract excerpt

Amyloid beta-protein (Abeta) assembly into toxic oligomeric and fibrillar structures is a seminal event in Alzheimer's disease, therefore blocking this process could have significant therapeutic benefit. A rigorous mechanistic understanding of Abeta assembly would facilitate the targeting and des...

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Source

Identifiers

PMID: 11580253
DOI: 10.1006/jmbi.2001.4970

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11580253-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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