Article
Impaired rescue of chain-terminated DNA synthesis associated with the L74V mutation in human immunodeficiency virus type 1 reverse transcriptase.
Antimicrobial agents and chemotherapy - 1 Jul 2005
Frankel Fernando A, Marchand Bruno, Turner Dan, Götte Matthias, Wainberg Mark A
Abstract excerpt
The L74V and M184V mutations in the reverse transcriptase (RT) gene of human immunodeficiency virus type 1 (HIV-1) are frequently associated with resistance to the nucleoside reverse transcriptase inhibitors abacavir, didanosine, and lamivudine. Yet viruses containing any of these mutations often...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.