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Article

Large-scale modelling as a route to multiple surface comparisons of the CCP module family

23 Jun 2005

Abstract excerpt

Numerous mammalian proteins are constructed from a limited repertoire of module-types. Proteins belonging to the regulators of complement activation family--crucial for ensuring a complement-mediated immune response is targeted against infectious agents--are composed solely of complement control protein (CCP) modules. In the current study, CCP module sequences were grouped to allow selection of the most...

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PMID: 15976010
DOI: 10.1093/protein/gzi039

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