Article
Bovine ICM derived cells express the Oct4 ortholog.
Molecular reproduction and development - 1 Oct 2005
Yadav Prem S, Kues Wilfried A, Herrmann Doris, Carnwath Joseph W, Niemann Heiner
Abstract excerpt
The goal of this study was to define conditions for the successful isolation of embryonic stem cells from bovine blastocysts. Expression of the Pit-Oct-Unc (POU) transcription factor Oct4 was employed to monitor the pluripotent status of cultured cells. No expression of the previously identified bovine Oct4 pseudogene was found, and transcription of the Oct4 ortholog correlated with the proliferative potential of...
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