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Article

Ovine-Induced Pluripotent Stem Cells Can Contribute to Chimeric Lambs

1 Feb 2012

Abstract excerpt

Pluripotential stem cells from livestock offer an exciting prospect for the biotechnology industry. Applying strategies established for the derivation of murine induced pluripotential stem cells (iPSCs), we have isolated ovine iPSCs that can give rise to cells characteristic of all three germ cell layers both in vitro from embryoid bodies and in teratomas in vivo. Furthermore, although at a low level, these ovine...

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PMID: 22217199
DOI: 10.1089/cell.2011.0050

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