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Article

Improved success of myoblast transplantation in mdx mice by blocking the myostatin signal.

Transplantation - 27 Jun 2005

Benabdallah Basma F, Bouchentouf Manaf, Tremblay Jacques P

Abstract excerpt

BACKGROUND: : Duchenne muscular dystrophy (DMD) is caused by a dystrophin gene mutation. Transplantation of normal myoblasts results in long-term restoration of dystrophin. However, the success of this approach is compromised by the limited time of regeneration following muscle damage. Myostatin is known to be responsible for limiting skeletal muscle regeneration. Our purpose is to verify whether blocking the...

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Source

Identifiers

PMID: 15973171
DOI: 10.1097/01.tp.0000167379.27872.2b

Genes

DMD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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