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Article

Mutations of Nuclear and Mitochondrial Genomes as Potential Targets for the Treatment of Metabolic Syndrome.

Current pharmaceutical design - 1 Jan 2018

Galitsyna Elena V, Zhelankin Andrey V, Sobenin Igor A, Orekhov Alexander N

Abstract excerpt

In addition to external factors, such as exercise, food and the environment, genetic predisposition makes great contribution to the development of metabolic disorders and cardiovascular disease. This review is aimed to examine the genetic basis of complex metabolic disorders conventionally described as "metabolic syndrome" (MetS), with the special focus on currently known mutations in the nuclear and...

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PMID: 29336249
DOI: 10.2174/1381612824666180115120725

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