Article
Synaptic dysfunction in Huntington's disease: a new perspective.
Cellular and molecular life sciences : CMLS - 1 Sept 2005
Smith R, Brundin P, Li J-Y
Abstract excerpt
Huntington's disease (HD) is caused by a polyglutamine expansion in the protein huntingtin and is characterized by intraneuronal inclusions and widespread neuronal death at the late stage of the disease. In research, most of the emphasis has been on understanding the cell death and its mechanisms. Until recently, it was believed that the vast majority, if not all, of the symptoms in HD are a direct consequence of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.