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Article

Negative cooperativity of uric acid binding to the transcriptional regulator HucR from Deinococcus radiodurans.

Journal of molecular biology - 22 Jul 2005

Wilkinson Steven P, Grove Anne

Abstract excerpt

Members of the MarR family of winged helix transcriptional regulators have been shown to regulate multidrug and oxidative stress response, pathogenesis, and catabolism of aromatic compounds. Many respond to anionic lipophilic compounds in their capacity to bind DNA, and the co-crystal structure o...

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Source

Identifiers

PMID: 15967460
DOI: 10.1016/j.jmb.2005.05.027

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15967460-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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