Article
The HIV-1 leader RNA conformational switch regulates RNA dimerization but does not regulate mRNA translation.
Biochemistry - 28 Jun 2005
Abbink Truus E M, Ooms Marcel, Haasnoot P C Joost, Berkhout Ben
Abstract excerpt
The untranslated leader RNA is the most conserved part of the human immunodeficiency virus type I (HIV-1) genome. It contains many regulatory motifs that mediate a variety of steps in the viral life cycle. Previous work showed that the full-length leader RNA can adopt two alternative structures:...
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