Article
Haplotype diversity in 11 candidate genes across four populations.
Genetics - 1 Sept 2005
Beaty T H, Fallin M D, Hetmanski J B, McIntosh I, Chong S S, Ingersoll R, Sheng X, Chakraborty R, Scott A F
Abstract excerpt
Analysis of haplotypes based on multiple single-nucleotide polymorphisms (SNP) is becoming common for both candidate gene and fine-mapping studies. Before embarking on studies of haplotypes from genetically distinct populations, however, it is important to consider variation both in linkage disequilibrium (LD) and in haplotype frequencies within and across populations, as both vary. Such diversity will influence...
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