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Article

Viral kinetics in patients with lamivudine-resistant hepatitis B during adefovir-lamivudine combination therapy.

Journal of hepatology - 1 Aug 2005

Mihm Ulrike, Gärtner Barbara Christine, Faust Dominik, Hofmann Wolf Peter, Sarrazin Christoph, Zeuzem Stefan, Herrmann Eva

Abstract excerpt

BACKGROUND/AIMS: Mathematical analysis of viral kinetics during lamivudine-adefovir combination therapy has not yet been performed in patients with lamivudine-resistant hepatitis B. METHODS: In 8 patients with lamivudine-resistant hepatitis B, adefovir dipivoxil (10 mg/day) was added to ongoing lamivudine. Viral decay during the first 8 weeks of combination therapy was described by a biphasic model to determine...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15964093
DOI: 10.1016/j.jhep.2005.02.037

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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