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Article

Analysis of pathological defects in methionine metabolism using a simple mathematical model.

Biochimica et biophysica acta - 25 Sept 2005

Prudova Anna, Martinov Mikhail V, Vitvitsky Victor M, Ataullakhanov Fazoil I, Banerjee Ruma

Abstract excerpt

Derangements in methionine metabolism are a hallmark of cancers and homocystinuria, an inborn error of metabolism. In this study, the metabolic consequences of the pathological changes associated with the key pathway enzymes, methionine adenosyl transferase (MAT), glycine N-methyl transferase (GNMT) and cystathionine beta-synthase (CBS) as well as an activation of polyamine metabolism, were analyzed using a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15963701
DOI: 10.1016/j.bbadis.2005.04.008

Genes

CBS
GNMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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