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Article

Cytochromes P450 and <i>MDR1</i> mRNA expression along the human gastrointestinal tract

30 Mar 2005

Abstract excerpt

AIM: The aim of this study was to quantify the mRNA expression of three cytochromes P450 (CYP) and P-glycoprotein (P-gp) in the human gastrointestinal (GI) tract. METHOD: Biopsies were obtained from gastric, duodenal, colonic and rectal mucosa during routine gastro-colonoscopy in 27 patients. The biopsies were snap-frozen in liquid nitrogen. Real-time reverse transcriptase-polymerase chain reaction (RT-PCR) was...

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PMID: 15963094
DOI: 10.1111/j.1365-2125.2005.02389.x

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