Article
Clinical value of genetically diagnosed lymph node micrometastasis for patients with oral squamous cell carcinoma.
Head & neck - 1 Aug 2005
Yamazaki Yutaka, Chiba Itsuo, Hirai Atsuko, Satoh Chiharu, Sakakibara Noriyuki, Notani Ken-ichi, Iizuka Tadashi, Totsuka Yasunori
Abstract excerpt
BACKGROUND: The purpose of this study was to investigate the incidence and clinical significance of genetically diagnosed lymph node micrometastasis for patients with oral squamous cell carcinoma (SCC). METHODS: A total of 495 lymph nodes obtained from 21 patients with primary oral SCCs that had p53 mutations were examined for corresponding p53 mutations in lymph nodes using mutant allele-specific amplification...
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