Article
p53 gene mutation in 150 dissected lymph nodes in a patient with esophageal cancer.
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus - 1 Oct 1998
Kajiyama Y, Kanno H, Ueno M, Udagawa H, Tsutsumi K, Kinoshita Y, Nakamura T, Akiyama H, Miwa S, Tsurumaru M
Abstract excerpt
For thoracic esophageal cancer, we perform extended three field lymph node dissection, and have achieved nearly 50% of overall 5-year survival. However, patients sometimes develop lymph node recurrences in spite of having no lymph node metastases found by conventional histopathologic examination. In a patient with esophageal squamous cell carcinoma, we sequenced all the p53 cDNA translated regions (exon 2-10) of...
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