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Systematic analysis of viral genes responsible for differential virulence between American and Australian West Nile virus strains

28 Jan 2015

Abstract excerpt

A variant Australian West Nile virus (WNV) strain, WNVNSW2011, emerged in 2011 causing an unprecedented outbreak of encephalitis in horses in south-eastern Australia. However, no human cases associated with this strain have yet been reported. Studies using mouse models for WNV pathogenesis showed that WNVNSW2011 was less virulent than the human-pathogenic American strain of WNV, New York 99 (WNVNY99). To identify...

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PMID: 25626681
DOI: 10.1099/vir.0.000069

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