Article
Screening for ZNF230 gene mutation and analysis of its correlation with azoospermia.
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Jun 2005
Dong Jing-tao, Zhang Si-zhong, Ma Yong-xin, Yang Kai-xuan, Huang Ming-kong, Sun Yan, He Guo-ping, Li Ya, Zhang Wei, Peng Yan
Abstract excerpt
OBJECTIVE: To investigate the possible association between ZNF230 gene and azoospermia. METHODS: Screening for mutation of all 6 exons of ZNF230 gene was performed by denaturing high performance liquid chromatography(DHPLC) in 99 patients with azoospermia and in 115 healthy men as controls. RESULTS: An A-->G transition at nucleotide 316 in exon 6 was identified. There were significant differences in the...
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