Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SISE matters: the sum of information on seventy-yr-old equivalents measures pedigree information content when assessing the risk of HNPCC in a family.

Familial cancer - 1 Jan 2005

Green R C, McLaughlin J R, Younghusband H B

Abstract excerpt

Hereditary non-polyposis colon cancer (HNPCC) is a significant cause of colorectal and other malignancies. Due to the lack of features that reliably differentiate between a sporadic case and an inherited case of colon cancer, it is likely that HNPCC is under reported. The diagnosis of HNPCC relies heavily on finding multiple cases of colorectal or other specific cancers within a family. In the absence of a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Aged
Share to Colorectal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms, Hereditary Nonpolyposis

Share to Models, Statistical

Share to Pedigree

Share to Risk Factors

Share to Sensitivity and Specificity

Source

Identifiers

PMID: 15951969
DOI: 10.1007/s10689-004-7251-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

SISE matters: the sum of information on seventy-yr-old equivalents measures pedigree information content when assessing the risk of HNPCC in a family.PMID 15951969Read ↗

Limitations of family cancer history assessment at initial surgical consultation.Semantic proximity Read ↗

Breast and bowel cancers diagnosed in people 'too young to have cancer': A blueprint for research using family and twin studies.Semantic proximity Read ↗

Estimating penetrance from multiple case families with predisposing mutations: extension of the 'genotype-restricted likelihood' (GRL) method.Semantic proximity Read ↗

Family and personal history in colorectal cancer patients: what are we missing?Semantic proximity Read ↗

Bayesian modeling for genetic anticipation in presence of mutational heterogeneity: a case study in Lynch syndrome.Semantic proximity Read ↗

Information recovery in cancer families: value for risk estimations.Semantic proximity Read ↗

Cost-Effectiveness of Personalized Screening for Colorectal Cancer Based on Polygenic Risk and Family History.Semantic proximity Read ↗

Evidence for a heritable contribution to neuroendocrine tumors of the small intestine.Semantic proximity Read ↗

Knowledge about hereditary nonpolyposis colorectal cancer; mutation carriers and physicians at equal levels.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.