Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A physiologic three-dimensional cell culture system to investigate the role of decorin in matrix organisation and cell survival.

Biochemical and biophysical research communications - 15 Jul 2005

Seidler Daniela G, Schaefer Liliana, Robenek Horst, Iozzo Renato V, Kresse Hans, Schönherr Elke

Abstract excerpt

In vivo cells exist in a three-dimensional environment generated and maintained by multiple cell-cell and cell-matrix interactions. Proteoglycans, like decorin, affect these complex interactions. Thus, we sought to investigate the role of decorin in a three-dimensional environment where the matrix was generated over time by decorin-deficient fibroblasts in the presence of L-ascorbic acid 2-phosphate. The cells...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ascorbic Acid
Share to Caspase 3

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Caspase 8

Share to Caspases

Share to Collagen Type I

Share to Collagen Type V

Share to Decorin

Share to Proteoglycans

Source

Identifiers

PMID: 15949467
DOI: 10.1016/j.bbrc.2005.04.175

Genes

FGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A physiologic three-dimensional cell culture system to investigate the role of decorin in matrix organisation and cell survival.PMID 15949467Read ↗

Syndecan-2 and decorin: proteoglycans with a difference--implications in keloid pathogenesis.Semantic proximity Read ↗

Differential interactions of decorin and decorin mutants with type I and type VI collagens.Semantic proximity Read ↗

The glycosaminoglycan chain of decorin plays an important role in collagen fibril formation at the early stages of fibrillogenesis.Semantic proximity Read ↗

Role of Decorin in the Lens and Ocular DiseasesSemantic proximity Read ↗

The role of decorin in collagen fibrillogenesis and skin homeostasis.Semantic proximity Read ↗

Decorin Interacts with Connective Tissue Growth Factor (CTGF)/CCN2 by LRR12 Inhibiting Its Biological ActivitySemantic proximity Read ↗

Decreased decorin expression in the tumor microenvironmentSemantic proximity Read ↗

Decorin counteracts disease progression in mice with recessive dystrophic epidermolysis bullosaSemantic proximity Read ↗

Decorin Promotes Nascent Proteoglycan Retention in Cartilage Matrix by Strengthening Collagen II-Aggrecan IntegrationSemantic proximity Read ↗

Matrix deposition by a calcifying human osteogenic sarcoma cell line (SAOS-2).Semantic proximity Read ↗

Decorin transfection suppresses profibrogenic genes and myofibroblast formation in human corneal fibroblastsSemantic proximity Read ↗

An anti-oncogenic role for decorin. Down-regulation of ErbB2 leads to growth suppression and cytodifferentiation of mammary carcinoma cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.