Article
Syndecan-2 and decorin: proteoglycans with a difference--implications in keloid pathogenesis.
The Journal of trauma - 1 Apr 2010
Mukhopadhyay Anandaroop, Wong Man Yi, Chan Sui Y, Do Dang V, Khoo Audrey, Ong Chee T, Cheong Han H, Lim Ivor J, Phan Thang T
Abstract excerpt
BACKGROUND: Growth factors and cytokines involved in the wound healing process seem to be immobilized at the cell surface and extracellular matrix via binding with proteoglycans, making them important modulators of cell dynamics. Our aim was to investigate the expression of two proteoglycans, namely syndecan-2 and decorin, and to elucidate their role in the pathogenesis of an aberrant wound healing process...
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