Article
A novel assay for protein phosphatase 2A (PP2A) complexes in vivo reveals differential effects of covalent modifications on different Saccharomyces cerevisiae PP2A heterotrimers.
Eukaryotic cell - 1 Jun 2005
Gentry Matthew S, Li Yikun, Wei Huijun, Syed Farhana F, Patel Sameer H, Hallberg Richard L, Pallas David C
Abstract excerpt
Protein phosphatase 2A (PP2A) catalytic subunit can be covalently modified at its carboxy terminus by phosphorylation or carboxymethylation. Determining the effects of these covalent modifications on the relative amounts and functions of different PP2A heterotrimers is essential to understanding how these modifications regulate PP2A-controlled cellular processes. In this study we have validated and used a novel...
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