Article
Saccharomyces cerevisiae homologs of mammalian B and B' subunits of protein phosphatase 2A direct the enzyme to distinct cellular functions.
The Journal of biological chemistry - 28 Mar 1997
Zhao Y, Boguslawski G, Zitomer R S, DePaoli-Roach A A
Abstract excerpt
Protein phosphatase 2A (PP2A) is a major cellular serine/threonine protein phosphatase, present in the cell in a variety of heterotrimeric forms that differ in their associated regulatory B-subunit. Cloning of the mammalian B' subunit has allowed the identification of a highly homologous Saccharomyces cerevisiae gene, RTS1. Disruption of the gene results in a temperature-sensitive growth defect that can be...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
