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Article

Effect of alphaIIb Ala477Pro(A446P) mutation of the platelet glycoprotein on the expression of alphaIIbbeta3 complex.

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences - 1 Aug 2009

Yuan Xiaoyu, Chen Fangping, Xia Kun, Fu Gan, Jian Zaifu, Jie Qinzhi, Wang Guangping

Abstract excerpt

OBJECTIVE: To explore the effect of glycoprotein (GP) alphaIIb Ala477Pro(A446P) mutation on the expression of integrin alphaIIbbeta3. METHODS: The alphaIIbA477P (A446P) eukaryotic expression plasmid alphaIIbA477P (A446P)-pcDNA3.1(+) was constructed by site-directed mutagenesis. Cos-7 cells were t...

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PMID: 19734576

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19734576-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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